The great cholesterol myth; unfortunate consequences of Brown and Goldstein’s mistake

as posted here.

This post directs to an ‘Oxford Journals‘ article, author Dr Duncan Adams, Faculty of Medicine, University of Otago, discussing in detail the issue of the incorrect conclusion about blood cholesterol levels, even when fine-tuned down to the LDL component, being a major cause of arterial congestion.

Although there is a genuine association, high LDL level is shown to be an effect rather than a cause. Therefore, the practice of reducing LDL levels by medication is not justified and has brought about extensive prescribing of unnecessary risky medications such as statins, and misleading guidelines for dietary principles.

The following extracts present some main factors:

“Unfortunately, Brown and Goldstein failed to realize that it is the loss of a functional cholesterol receptor, causing impaired
ability to absorb and use cholesterol, which is the probable cause of the accelerated arteriosclerosis occurring in FH. Instead, they assumed that the cause is the high level of blood cholesterol, which ‘salts out’ into the arterial walls, causing the vascular impairment. This was an understandable mistake, because as mentioned above, the atheromatous plaques of arteriosclerosis contain cholesterol, which causes a bulge impinging on the lumen. In angioplasty, cardiologists use mechanical pressure to
flatten such bulges, with therapeutic benefit to the flow of blood. However, pathologists realize that deposition of cholesterol in the arterial walls seems to be secondary to hydrodynamic damage,7 followed by inflammation, with cell multiplication and somatic gene mutation.”

“Brown and Goldstein’s burst of fascinating information dazzled the medical profession, most of whom consequently accepted
the false cholesterol hypothesis. This has led to unfortunate consequences that include:

  1. Waste of money on misdirected research.

  2. Waste of money on blood cholesterol tests.

  3. Waste of money on statins.

  4. Malnutrition from lack of fat-soluble vitamins (A,D,K,E) present in butter, full-cream milk and animal fat but lacking in
    margarine and skim milk (green-top bottles in New Zealand).

  5. Fear of eating eggs, contributing to unhealthy, starchy diets.

  6. Ricketts in middle-aged men from lack of vitamin D due to use of margarine and skim-milk.

  7. Distortion of the Dairy Industry, causing unnecessary marketing of skim milk.

  8. Distortion of the Meat Industry with unnecessary production of lean meat.”

Unfortunately, although this is authentic medical opinion, it is swamped by the enormous, runaway inertia built up within the specialists, pharmaceutical and food manufacturer systems, as a result of the initial conclusions by Brown and Goldstein.

I am not aware of any particular paper that falsifies what Dr Adams is telling us. There is  a lot of other information here and on linked sites that instil confidence in publishing this reference to the ‘Oxford Journals-Medicine-QJM: An International Journal of Medicine-Volume 104, Issue 10- Pp. 867-870

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