A vaccine for heart disease?


Blood flow visualization

Blood flow visualization (Photo credit: Argonne National Laboratory)

The previous two posts relating to vaccinations have led me to a new site which has excited me. Readers will be aware of my personal health adventure with a cardiac event. Uncertainties about the relationships between cholesterol, cholesterol lowering drugs,(statins), and cardiac event risks have since been dogging me.

Although inflammation and its causes are sometimes cited as primary factors in artery blockages, never have I seen such a clear description of the real probable process involved.

“This is what makes the inflammation in the vessel wall persistent.” Inflammatory cells join fat and cholesterol to form artery-clogging plaque that can eventually block blood flow, leading to a heart attack.”

Usually cholesterol is cited as the major factor. Yet cholesterol, in general is essential to the body.  Reduction to cardiology recommended levels may statistically reduce cardiac event risks but seems to ignore possible adverse effects on other health issues. In order to achieve these low cholesterol levels, statins are very widely prescribed, yet introduce some serious side-effect issues.

It would be too simple to suggest that without artery inflammation there would be no fat and cholesterol build-up and subsequent blockage, but, the ball park is altered. It is likely that moderate amounts of cholesterol, which are good/essential for the body, would not cause cardiac events if the inflammation was non-existent.

So, I remain unconvinced of the need for statins, providing other measures are in place. This conviction ?unconviction, is strengthened by the “Medical Xpress” post “A vaccine for heart disease? New discovery points up this possibility”.

Most people probably know that heart disease remains the nation’s No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system

A number of research studies have demonstrated inflammation’s role in fueling plaque buildup, also known as atherosclerosis, which is the underlying cause of most heart attacks and strokes, but knowledge of which immune cells are key to this process has been limited – until now. Researchers at the La Jolla Institute for Allergy & Immunology have identified the specific type of immune cells (CD4 T cells) that orchestrate the inflammatory attack on the artery wall. Further, the researchers discovered that these immune cells behave as if they have previously seen the antigen that causes them to launch the attack. “The thing that excites me most about this finding is that these immune cells appear to have ‘memory’ of the molecule brought forth by the antigen-presenting cells,” said Klaus Ley, M.D., a renowned expert in vascular immunology, who led the study in mouse models. “Immune memory is the underlying basis of successful vaccines. This means that conceptually it becomes possible to consider the development of a vaccine for heart disease.”

Read the source post and view its video, to learn about the possible vaccine scenario, here.

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About Ken McMurtrie

Retired Electronics Engineer, most recently installing and maintaining medical X-Ray equipment. A mature age "student" of Life and Nature, an advocate of Truth, Justice and Humanity, promoting awareness of the injustices in the world.
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2 Responses to A vaccine for heart disease?

  1. Couple of comments Ken….. IF Inflammation is the underlying cause of plaque formation in the artery wall….. we still need to go back another step and ask what causes the inflammation? Of course I subscribe to bad diet as being one factor, plus the inherited genes some us are are unfortunate to have been born with.

    I sent you some papers from professor Uffe Ravnskov to stretch your imagination. In time you may find them beneficial to blog about. However lets us postulate on the bacterium theory leading to inflammation…. it is possible In the human body there are bacterial and microbes which are much smaller than those we previously blamed on di-ease. A reading up on the work of Dr. Garth Nicolson ( http://www.immed.org/illness/infectious_disease_research.html ) makes a facinating study.

    I also pass along a link that might stimulate interest. No matter what you think about Dwight Lundell he certainly asks you to THINK.

    http://www.laleva.org/eng/2012/03/world_renown_heart_surgeon_speaks_out_on_what_really_causes_heart_disease.html

    Second point I want to mention is that when people read VACCINE they instinctively think of the ones used on children such as mumps, chicken pox, whooping cough etc…. a once or maybe twice in a life time thing (which as you may well know I am seriously against)…. However this Proposed new drug would not be like that at all, it would probably be an ongoing medical tTreatment – possibly for life…….

    “Prof Nilsson said it was unlikely that the products would be given as traditional vaccines in early childhood and instead were more like drugs in that they would need to be given repeatedly.

    He said: “Both these treatments are far more like drugs – to be effective they’d need to be given long term. The antibody therapy in particularly is likely to be expensive so you could probably only afford to give it to high risk populations rather than everyone.”

    Professor Peter Weissberg, Medical Director at the British Heart Foundation said: “A vaccination approach to the treatment of atherosclerosis is based on an attempt to interfere with the cellular mechanisms that cause life threatening build up of fatty deposits.

    “There will be great interest in the outcome of the on-going studies to see firstly if this approach is safe and secondly, whether it can influence the progression of vascular disease in the long term.

    “It is very promising, but it will take some time before we know if it is successful and, if so, which patients are likely to benefit most from this treatment.” ”

    AGAIN as in all things follow the dollar…… this is NO CURE this is another money making scheme, keeping people as life long patients……

    OK off my soap box…… All the best.

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